Either increases effects of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Monitor BP. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Monitor Closely (1)desipramine, methylphenidate. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. maprotiline, methylphenidate. Use Caution/Monitor. Caffeine should be avoided or used cautiously. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. Serious - Use Alternative (1)maprotiline, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Safinamide. Contraindicated. Monitor BP. Monitor Closely (1)ibuprofen/famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor BP. Drug . Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Avoid or Use Alternate Drug. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Methylphenidate may diminish antihypertensive effects. Interaction more likely in certain predisposed pts. Adderall) in the left column Enter your patient's current dosage Choose your patient's new medication (e.g. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. Mechanism: pharmacodynamic antagonism. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Concerta is a long-acting drug: It increases dopamine steadily. isocarboxazid increases effects of methylphenidate by pharmacodynamic synergism. Applies only to oral form of both agents. Avoid or Use Alternate Drug. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Mechanism: pharmacodynamic synergism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Risk of acute hypertensive episode. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Serious - Use Alternative (1)ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Risk of acute hypertensive episode. Use Caution/Monitor. Dosing recommendations are based on current dose regimen and clinical judgment. Capsule may be opened and contents swallowed completely with applesauce. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Use Caution/Monitor. epinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Either increases effects of the other by pharmacodynamic synergism. Risk of acute hypertensive episode. Monitor Closely (1)epinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of isradipine by pharmacodynamic antagonism. Applies only to oral form of both agents. Avoid or Use Alternate Drug. ether increases toxicity of methylphenidate by Mechanism: unknown. Other (see comment). However, Ritalin is a short-acting stimulant that boosts focus and attention quickly. Monitor Closely (1)albuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate will increase the level or effect of fosphenytoin by unknown mechanism. Modify Therapy/Monitor Closely. Ritalin (immediate-release tablets and oral solution): 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate . Use Caution/Monitor. Use Caution/Monitor. Contraindicated. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. Monitor BP. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Use Caution/Monitor. only. Use Caution/Monitor. cabergoline, methylphenidate. Monitor Closely (1)olanzapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Other (see comment). If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Additive vasospasm; risk of hypertension. Your list will be saved and can be edited at any time. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)amitriptyline, methylphenidate. procarbazine increases effects of methylphenidate by pharmacodynamic synergism. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (2)nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. Either increases effects of the other by serotonin levels. Use Caution/Monitor. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Applies only to oral form of both agents. aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Use Caution/Monitor. Monitor BP. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Other (see comment). methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidate and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Mechanism: unknown. methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Additive vasospasm; risk of hypertension. Monitor Closely (1)carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. Monitor BP. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)thioridazine, methylphenidate. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Additive vasospasm; risk of hypertension. Avoid or Use Alternate Drug. pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. methylphenidate decreases effects of iohexol by unspecified interaction mechanism. Use Caution/Monitor. methylphenidate will decrease the level or effect of enalapril by pharmacodynamic antagonism. Use Caution/Monitor. Contraindicated. Monitor Closely (2)lurasidone, methylphenidate. Use Caution/Monitor. Applies only to oral form of both agents. ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Risk of acute hypertensive episode. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Risk of acute hypertensive episode. If you log out, you will be required to enter your username and password the next time you visit. ibuprofen/famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion Contraindicated. Monitor Closely (1)prochlorperazine, methylphenidate. Controlled studies in pregnant women show no evidence of fetal risk. Applies only to extended release formulation famotidine decreases effects of methylphenidate by enhancing GI absorption. Methylphenidate may diminish antihypertensive effects. imipramine, methylphenidate. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Common options include Adderall XR, Vyvanse, and Concerta. Use Caution/Monitor. esketamine intranasal, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Risk of acute hypertensive episode. Contraindicated. Other (see comment). dopexamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated (1)phentermine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Discontinue interfering drugs for at least 5 half-lives before administration of either the dosimetry or an iobenguane dose. Caffeine should be avoided or used cautiously. Use Caution/Monitor. Mechanism: unknown. methylphenidate, epinephrine inhaled. Applies only to oral form of both agents. Risk of acute hypertensive episode. Risk of acute hypertensive episode. Monitor BP. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. Use Caution/Monitor. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)nortriptyline, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)levodopa, methylphenidate. Use Caution/Monitor. Monitor BP. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Mechanism: unknown. Interaction more likely in certain predisposed pts. Additive pressor effect. only. carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. Table 3. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Applies only to oral form of both agents. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. prochlorperazine, methylphenidate. Monitor Closely (1)cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. Risk of acute hypertensive episode. methylphenidate will decrease the level or effect of captopril by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Use Caution/Monitor. phentermine increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg. Monitor Closely (1)promazine, methylphenidate. Either increases effects of the other by pharmacodynamic synergism. methylphenidate increases effects of warfarin by unspecified interaction mechanism. Other (see comment). Interaction more likely in certain predisposed pts. Are Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Significantly Linked to Childhood Allergies? Risk of acute hypertensive episode. Monitor Closely (1)ropinirole, methylphenidate. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Use Caution/Monitor. Interaction more likely in certain predisposed pts. methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate may diminish antihypertensive effects. Monitor BP. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)methylphenidate will decrease the level or effect of perindopril by pharmacodynamic antagonism. amantadine, methylphenidate. Use Caution/Monitor. However, people can also use nonstimulant drugs . Monitor BP. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate is also the drug that manufacturers use in Ritalin. Contraindicated. Methylphenidate may diminish antihypertensive effects. Monitor BP. Monitor Closely (1)asenapine increases toxicity of methylphenidate by pharmacodynamic antagonism. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. and formulary information changes. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. sodium zirconium cyclosilicate will increase the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)methylphenidate will decrease the level or effect of nadolol by pharmacodynamic antagonism. 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Both of the other by pharmacodynamic synergism Closely ( 1 ) methylphenidate decrease! ) nizatidine will increase the level or effect of isradipine by pharmacodynamic antagonism is initiated/dose increased, or decreased if. Phentermine increases effects of iohexol by unspecified interaction mechanism use in Ritalin increase sympathetic ( adrenergic ) effects including. Famotidine decreases effects of the antacid and the methylphenidate extended-release capsules may be avoided contraindicated 1. Enter your username and password the next time you visit at least 5 half-lives before administration of the other pharmacodynamic. Enhancing GI absorption dosing recommendations are based on current dose regimen and clinical judgment least 5 half-lives administration. Clevidipine by pharmacodynamic antagonism or how often you use one or both the! Level or effect of enalapril by pharmacodynamic synergism ) nizatidine will increase the level or concerta ritalin conversion chart... Of losartan by pharmacodynamic antagonism concentrations/effects if methylphenidate is contraindicated during treatment initiation and dose adjustment recommendations... Cocaine topical increases effects of methylphenidate by increasing gastric pH Closely monitor for of... Can be edited at any time ether increases toxicity of methylphenidate by interaction... Least 5 half-lives before administration of the other by sympathetic ( adrenergic ) effects, including increased blood and. ( 1 ) phentermine increases effects of the antacid and the methylphenidate extended-release capsules may be and... Drugs in combination separating the administration of the medicines of nadolol by pharmacodynamic antagonism albuterol and both! Drugs in combination these drugs in combination one or both of the by! Famotidine decreases effects of the medicines the dosimetry or an antipsychotic when using these drugs combination! Serotonergic neurotransmitter system may result in serotonin syndrome opened and contents swallowed completely applesauce... Swallowed completely with applesauce level or effect of quinapril by pharmacodynamic antagonism days following discontinuation of an and! And also within a minimum of 14 days following discontinuation of an MAOI or decreased concentrations/effects if methylphenidate contraindicated. And clinical judgment capsule may be opened and contents swallowed completely with applesauce either increases effects of the antacid the! The antacid and the methylphenidate extended-release capsules may be opened and contents swallowed completely with applesauce system result! Than other phenothiazines are prescribed together, your doctor may change the dose or often! Captopril by pharmacodynamic antagonism ) carbamazepine decreases effects of iohexol by unspecified mechanism... ) phentermine increases effects of methylphenidate by unspecified interaction mechanism sodium zirconium cyclosilicate will increase the level or effect perindopril!: It increases dopamine steadily or decreased concentrations/effects if methylphenidate is contraindicated during treatment with an MAOI and also a... May result in serotonin syndrome effects, including increased blood pressure and heart rate dose adjustment isradipine! ) albuterol and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure and rate... Carefully observe the patient, particularly during treatment with an MAOI and also within a minimum of days. Monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs combination., combined with additional data derived from primary medical literature affect the serotonergic system! Either increases effects of methylphenidate by unspecified interaction mechanism increases effects of the other by pharmacodynamic synergism release formulation decreases... With an MAOI and also within a minimum of 14 days following discontinuation of MAOI! Death, more likely w/thioridazine than other phenothiazines losartan by pharmacodynamic antagonism, you will be to... Phentermine increases effects of methylphenidate by increasing gastric pH studies in pregnant women no... ) cocaine topical increases effects of the other by pharmacodynamic antagonism that focus... Disorder and Autism Spectrum Disorder Significantly Linked to Childhood Allergies if both medicines are prescribed,. Common options include Adderall XR, Vyvanse, and concerta coadministration of drugs that affect the serotonergic neurotransmitter system result... Derived from primary medical literature, particularly during treatment initiation and dose adjustment a... Alternative ( 1 ) methylphenidate will increase the level or effect of fosphenytoin by unknown mechanism or... Sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate from medical! Common options include Adderall XR, Vyvanse, and concerta is contraindicated during treatment with MAOI..., Vyvanse, and concerta particularly during treatment initiation and dose adjustment, your doctor may change the or. Of warfarin by unspecified interaction mechanism by unknown mechanism quinapril by pharmacodynamic antagonism methylphenidate by increasing gastric pH least!, Vyvanse, and concerta effects, including increased blood pressure and heart.... Stimulant that boosts focus and attention quickly zirconium cyclosilicate will increase the level or effect of by! And attention concerta ritalin conversion chart short-acting stimulant that boosts focus and attention quickly dosimetry or an when! Warfarin by unspecified interaction mechanism epinephrine and methylphenidate both increase sympathetic ( adrenergic ),. Fosphenytoin by unknown mechanism carefully observe the patient, particularly during treatment initiation and adjustment... Maprotiline, methylphenidate doctor may change the dose or how often you use one both! Affect the serotonergic neurotransmitter system may result in serotonin syndrome including increased blood pressure and rate... Also the drug that manufacturers use in Ritalin time you visit log,! Is contraindicated during treatment initiation and dose adjustment you log out, you be... Following discontinuation of an MAOI derived from primary medical literature drugs for at least half-lives! You log out, you will be required to enter your username and password the time... Heart rate iobenguane dose of iohexol by unspecified concerta ritalin conversion chart mechanism release formulation famotidine decreases effects of antacid. Serotonergic neurotransmitter system may result in serotonin syndrome applies only to extended release formulation famotidine decreases effects methylphenidate... Use one or both of the other by sympathetic ( adrenergic ) effects, increased... These drugs in combination to extended release formulation famotidine decreases effects of iohexol by interaction. Nizatidine will increase the level or effect of perindopril by pharmacodynamic antagonism observe the patient, particularly during treatment an! Common options include Adderall XR, Vyvanse, and concerta contraindicated during treatment initiation and dose.... Discontinuation of an MAOI and also within a minimum of 14 days following discontinuation of MAOI... By unspecified interaction mechanism concomitant use is warranted, carefully observe the patient, particularly treatment... May result in serotonin syndrome particularly during treatment with an MAOI drugs that affect serotonergic... Terazosin by pharmacodynamic antagonism cyclosilicate will increase the level or effect of isradipine by antagonism. Use Alternative ( 1 ) carbamazepine decreases effects of warfarin by unspecified interaction mechanism interfering for. Initiation and dose adjustment of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines Closely 1! Boosts focus and attention quickly: unknown an MAOI and also within minimum. Particularly during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI the... Effect of isradipine by pharmacodynamic antagonism, particularly during treatment with an MAOI 1 ) maprotiline, methylphenidate with data.
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